产品货号:
Z26951
中文名称:
SODD/BAG4抗体
英文名称:
Anti-SODD/BAG4 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SODD/BAG4 Antibody |
指标别名 | BAG 4;BAG4;Silencer of death domains;SODD |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | BAG4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from the C-terminal region of human Bag-4. |
计算分子量 | 50KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors,TNF-R1 and Fas.Several novel death receptors including DR3,DR4,DR5,and DR6 were recently identified.Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors.A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains.SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling.TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex,which activates TNF signaling pathways.SODD also interacts with DR3.SODD is ubiquitously expressed in human tissues and cell lines. |
Uniprot ID | O95429 |
基因名全称 | BAG family molecular chaperone regulator 4 |
推荐稀释比 | WB,1:500~1:2000 |
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